Procedure Offers New Hope for Patients with Chronic Obstructive Pulmonary Disease

OSU Medical Center and OSU Center for Health Sciences Partner in Clinical Research Study

Oklahoma State University Medical Center is pleased to announce its partnership with the OSU Center for Health Sciences in conducting a clinical research study targeted at patients who suffer from severe Chronic Obstructive Pulmonary Disease (COPD.

OSU Medical Center is one of nine sites across the nation chosen to host the clinical trial which involves the use of a novel medical device known as an Anastomotic Coupler System (ACS). The study is sponsored by ROX Medical, Inc.

“The other sites at which this research is taking place are large metropolitan medical centers such as University of California, Los Angeles Medical Center,” said Jan Slater, OSU Medical Center chief executive officer. “We were chosen based on Dr. Daniel Nader’s experience and reputation in pulmonary device trials and the fact that we have the patient population to support this work.”

Patients must have a diagnosis of advanced Chronic Obstructive Pulmonary Disease (COPD), complete a course of pulmonary rehabilitation and undergo several medical tests before qualifying for the procedure. Once eligible for the procedure, half of the patients will receive the ACS, a small alloy metal implant which creates a connection between a specific artery and vein, allowing more oxygenated blood to quickly return to the lungs. The other half of the patients will be assigned to the control group, and will continue to be treated only with medical therapy. Those patients who participate in the control group for one year may be eligible to receive the device if they still qualify.

“The first Oklahoma patient received the medical device at OSU Medical Center on Dec. 18, 2009. We will follow the patient’s progress for the next several years,” said OSU Center for Health Sciences principal investigator, Dr. Daniel Nader.

The device is intended for patients who use supplemental oxygen due to significant shortness of breath. Potential benefits may include improved breathing and exercise capacity. Patients may be able to walk farther and quality of life may improve.

Daniel A. Nader, D.O., pulmonologist, is the medical director of the Center for Respiratory Medicine and assistant professor of Internal Medicine at the OSU Center for Health Sciences. He and study coordinators, Diana Tameny, C.R.T. and Mary Donovan, C.C.R.C., work together to identify and screen potential patients.

Michael P. Carney, D.O., cardiologist and adjunct clinical assistant professor of Internal Medicine at OSU Center for Health Sciences College of Osteopathic Medicine, and Dr. George Erbacher, D O., interventional radiologist at the OSU Medical Center and clinical assistant professor of surgery at the OSU Center for Health Sciences, work together to perform the coupling procedures and implant the device.

The clinical trial, called “The WALK Trial,” is enrolling until summer 2010. More information can be found at Patients also can visit the website and type “emphysema Oklahoma” in the search box or call the OSU Physician’s Center for Respiratory Medicine at (918) 584-5336.

George E. Erbacher, D.O., Michael P. Carney, D.O., Jan Slater, CEO OSU Medical Center, Daniel A. Nader, D.O.


OSU Medical Center has offered exceptional health care for 65 years. Located in downtown Tulsa, the hospital is the largest osteopathic teaching facility in the country, boasting 11 post-graduate programs that train more than 140 residents each year in both primary care and sub-specialty areas. Together, the school and hospital have trained more than 2,000 physicians, of which more than 900 are actively practicing in Oklahoma.

OSU Medical Center provides numerous highly specialized services, including cardiology care, interventional radiology, and comprehensive wound care. The hospital also partners with OSU Center for Health Sciences and Diagnostic Imaging Associates to provide medical care to Oklahoma’s rural communities with a telemedicine program. This telemedicine program currently includes 36 regional hospital and clinic partners, the largest state-wide telemedicine program in the nation.

OSU Medical Center is owned by a City of Tulsa trust called OSU Medical Center Trust, and managed by St. John Health System.

For more about OSUMC, visit

About OSU Center for Health Sciences

Oklahoma State University Center for Health Sciences in Tulsa offers programs in osteopathic medicine, biomedical sciences and forensic sciences. Since its beginnings more than 30 years ago, OSU-CHS has grown to offer eight graduate degrees. On-campus programs, distance learning and OSU partnerships train osteopathic physicians, research scientists and health care professionals with an emphasis on serving rural and under-served Oklahoma. OSU operates clinics in Tulsa and Enid. More information about OSU Center for Health Sciences is available at